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Oral administration of phenacetin at doses of 600 to 1200 mg/kg bw/d from gestational days 0 to 20 is reportedly associated with reduced fetal weight, although the magnitude of the effect is not stated (Baethke and Muller 1965 as cited in IARC 1980). Effects of Baicalin on Phenacetin Pharmacokinetics in Rats in vivo.